Role of Alpha Fetoprotein in Hepatocellular Carcinoma
نویسندگان
چکیده
منابع مشابه
Excessive alpha-fetoprotein concentrations in hepatocellular carcinoma.
Excessive alpha-fetoprotein concentrations in hepatocellular carcinoma We describe a patient with hepatocellular carcinoma, whose serum concentration of ac-fetoprotein exceeded 4 800 000 ,ug/l and produced an extra band on protein electrophoresis. complaining of severe right shoulder pain and abdominal distension of about two weeks' duration. He had a massively enlarged liver with considerable ...
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Hepatocellular carcinoma (HCC) is one of the leading causes of liver transplantation. In an attempt to predict their recurrence after liver transplantation, evaluation of tumor number and size, degree of histologic differentiation, and the presence of vascular invasion already have their importance established. In this context, the role of biologic markers such as alpha-fetoprotein (AFP) is sti...
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Alpha-fetoprotein (AFP)-producing esophageal adenocarcinoma (EAC) is a rare occurrence. Elevation of serum AFP is commonly associated with hepatocellular carcinoma and yolk sac tumors, but rarely with esophageal carcinoma. Here, we report a rare case of AFP-producing EAC. A 51-year-old man presented with two weeks of acid reflux and a 35-lb weight loss. Laboratory data were notable for transami...
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A high level of serum alpha fetoprotein (AFP) is positively associated with human hepatocellular carcinoma (HCC) carcinogenesis and metastasis; however, the function of AFP in HCC metastasis is unknown. This study has explored the effects of AFP on regulating metastatic and invasive capacity of human HCC cells. Forty-seven clinical patients' liver samples were collected and diagnosed; HCC cells...
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The majority of human hepatocellular carcinomas overexpress alpha-fetoprotein (AFP). Two genetic immunization strategies were used to determine whether AFP could serve as a target for T-cell immune responses. Dendritic cells engineered to express AFP produced potent T-cell responses in mice, as evidenced by the generation of AFP-specific CTLs, cytokine-producing T cells, and protective immunity...
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ژورنال
عنوان ژورنال: Cancer Studies and Therapeutics
سال: 2022
ISSN: ['2002-7184']
DOI: https://doi.org/10.31038/cst.2022723